![]() ![]() Both diseases are recessive, meaning that dogs must have two copies of the mutation to be affected with either of these diseases. PPG has launched two additional disease tests for Labrador retrievers, Cone Degeneration and Stargardt Disease. Testing a dog for the Intensity locus may help breeders identify carriers (I/i) from non carriers (I/I) or identify the genetic basis for dogs that have a lighter coat color as compared to littermates or others of the same breed. Dogs that are e/e at the E locus, are sable, or have tan points due to the A locus, may show a lighter color only where the phaeomelanin pigment is expressed if they carry two copies of the Intensity variant (i/i). The Intensity locus can modify the yellow or red phaeomelanin pigment to a less intense, cream or white. ![]() As Saddle Tan is dominant, testing for this variant will reveal if a dog has one or two copies of this variant. Sometimes called creeping tan, a dog with one or two copies of the A s variant and tan points may show a ‘shrinking’ dark saddle across the back, revealing more of the tan points. For Saddle Tan, the variation in the RALY gene will modify a dog’s coat presentation only if the dog also has tan points (k yk y at the K locus and a t/a t or a t/a at the A locus). Both of these genetic loci modify a dog’s coat color based on their genotypes at other coat color genes. PPG has launched Saddle Tan (A s locus) and Intensity (I locus) as part of their large number of coat colors and traits offered for various breeds. You can find these new tests for your breed under the category “Additional Disease Tests” on your breed-specific page on our website. Here are some of the new tests being offered. With nearly 300 different tests for more than 350 breeds of dog, Paw Print Genetics (PPG) continues to be the leader in providing genetic tests for dogs. Paw Print Genetics has launched 44 new inherited disease tests and two new trait tests for various breeds. ![]()
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